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Symbol
Name
ID
Cldn11
claudin 11
MGI:106925
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Drooling
CNS hypomyelination
Babinski sign
Delayed speech and language development
Dysarthria
Intellectual disability, borderline
Lower limb hyperreflexia
Inability to walk
Delayed ability to sit
Delayed ability to walk
Disease(s) Associated with CLDN11
hypomyelinating leukodystrophy 22

Mouse Phenotypes
nervous system phenotype
cochlear outer hair cell degeneration
abnormal myelin sheath morphology
Availability Mouse Genotype
Cldn11tm1Ral/Cldn11tm1Ral *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory